Tuesday, January 26, 2016

Epidemiology

The distribution of increased incidence positively correlates with the increase of prescription drug use. The map below represents the cases of Neonatal Abstinence Syndrome in each state. This was based off of the analysis of the Kids' Inpatient Sample 2012 (Vanderbilt, 2012).
When looking at the map above, Kentucky, Tennessee, Mississippi, and Alabama are the states with the highest incidence of Neonatal Abstinence Syndrome at 16.2 births per 1000 births. This correlates with the amount of Opiate medications being subscribed by medical professionals within the same time frame. The image below represents prescribing rates per 100 persons, in quartiles, by state and drug type during 2012; the south region had the highest rates of prescribing opioid pain relievers and benzodiazepines (Paulozzi, Mack & Hockenberry, 2014).
Over the last five years, Neonatal Abstinence Syndrome (NAS) has increased in the United States. From 2000 to 2012, there was a five-fold increase of infants born with NAS (National Institute on Drug Abuse, 2015). More often than not, people who are addicted to a substance are using multiple. This brings even more risk to the infant who could need numerous detox regimens. NAS is rarely fatal because the infants are taken into critical care and are given the appropriate measures when diagnosed (Kocherlakota, 2014). In an experiment based in Florida, mothers with infants diagnosed with NAS, were on a combination of Opioids, Benzodiazepines, Tobacco, Marijuana, Cocaine, Antidepressants, Barbiturates, Methamphetamine, and Alcohol (Lind, Petersen, Lederer, Phillips-Bell, Perrine, Li, . . . Anjohrin, 2015). When focusing on the Opiate use, the mothers shared different reasons for using, these included; illicit use, drug abuse treatment, chronic pain or unknown (Lind et al., 2015). Populations at greater risk for abusing drugs include: those treating chronic pain, seeking thrill, or treating their tolerance (Women's Health Care Physicians, 2012). When looking at the research study, ethnically the majority of mothers identified as White, non-Hispanic, then followed Hispanic, Black, non-Hispanic and other (Lind et al., 2015). The results in this study are limited to Florida, but it gives a good picture of what is going on with the mothers with infants diagnosed with Neonatal Abstinence Syndrome. 

 Search terms: Neonatal Abstinence Syndrome, Epidemiology, Nationwide


 References

Kocherlakota, P. (2014). Neonatal Abstinence Syndrome. Pediatrics, 134(2). 

Lind, J., Petersen, E., Lederer, P., Phillips-Bell, G., Perrine, C., Li, R., . . . Anjohrin, S. (2015). Infant and Maternal Characteristics in Neonatal Abstinence Syndrome — Selected Hospitals in Florida, 2010–2011. Morbidity and Mortality Weekly Report, 64(8), 213-216.

National Institute on Drug Abuse (2015). Dramatic increases in maternal opioid use and neonatal abstinence syndrome.  Retrieved January 20, 2016, from http://www.drugabuse.gov/related-topics/trends-statistics/infographics/dramatic-increases-in-maternal-opioid-use-neonatal-abstinence-syndrome

Paulozzi, L. J., Mack, K. A., & Hockenberry, J. M. (2014). Variation among states in prescribing of opioid pain relievers and benzodiazepines — United States, 2012. Journal of Safety Research, 51, 125-129.

Vanderbilt. (2012). Neonatal Abstinence Syndrome. Retrieved January 26, 2016, from https://medschool.vanderbilt.edu/nas/

Women's Health Care Physicians. (2012). Retrieved January 26, 2016, from http://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Health-Care-for-Underserved-Women/Opioid-Abuse-Dependence-and-Addiction-in-Pregnancy

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